Cell Biology

Mendelian Inheritance in Man (OMIM): (database of human genetic diseases and genetic variants) See also DNA Introduction/Definitions: When defining the number of chromosomes necessary to define  a species, geneticits count…

The plasma membrane of all electrically excitable cells such as neurons contain voltage gated cation channels which are responsible for generating an action potential which is a traveling wave of electrical excitation. An action…

Introduction: Cell membranes are not permeable to all molecules. Small molecules like oxygen and carbon dioxide diffuse rapidly across membranes. Small uncharged polar molecules like water or urea diffuse more…

Cell membranes consist of a continuous double layer of lipid molecules in which membrane proteins are embedded. Lipids constitute about 50% of the mass of most animal cell membranes with…

See also the Cell Cycle See also Cancer Disease Mechanisms See also signal transduction Controling the process of cell division is critical. Loss of this control can lead to cancer.  The…

See also cell cycle control Introduction/Definitions: Progression through the cell cycle requires the coordination of  variety of macromolecular syntheses, assemblies and movements. The chromosomes must be replicated, condensed, segregated, and…

The caspases, comprising a family of cysteine proteases, have been firmly established as major mediators of the execution phase of apoptosis. While most of the known CASPs are involved in…

Introduction: Pathways for apoptosis induction or inhibition originate from both extrinsic and intrinsic signalling systems. Extrinsic signalling pathways are initiated by ligand binding to cell-surface receptors (e.g., Fas ligand binding…

See also  Apoptosis Assays Introduction: Apoptosis, or programmed cell death, is a process fundamental to the normal development and homeostasis of multicellular organisms. Deregulation of programmed cell death leads to a number…

Integrins are widely expressed cell surface adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. Integrins are the principal receptors on animal cells for binding most  like collagens, fibronectin and laminins. T…