polyclonal antibody production

To constrain costs, strategies have been developed to produce recombinant polyclonal antibodies in a single pot. This process by passes the manufacturing hurdles assocaited with individual antibody production but introduces…

Common Analytical Techniques

  Differential scanning calorimetry (DSC) can be used to examine the stability of the tertiary structure of antibody preparations. (Brass, Pharm Acta Helv. 1996, 71(6): 395-403)  Immunoassay (ELISA): can be used to…

Waste Water Treatment

Septic Systems Many rural and suburban areas rely on septic tanks which are containers into which sewage flows. The solid material settles and is subject to microbial decomposition. The liquid…

Peptides and Mimotopes

Companies: Abreos Biosciences Links of interest: Mimo DB Definitions Anti-Idiotype antibody: binds to the idiotype of another antibody, usually an antibody drug.  Idiotype: is the sepcific combination of idiotopes present…

Blood Purification

Companies:  Haemonetics Apheresis (cytapheresis and Plasmapheresis): Conventional apheresis methods include centrifugation, which can separate any of the components of the blood, and membrane filtration, which can be used for plasmapheresis…

Protein L

See also Continuous Chromatography under Chromatography, Column arrangement. Commercial Protein L Resins: Capto L (GE Healthcare Life Sciences) Data file 29-0100-08 AB) combines a rigid, high flow agarose matrix with…

Depth Filtration

companies: 3M filtration See also depth filters generally Despite low shear centrifuge designs, the centrate effluent may still contain appreciable amounts of smaller sized contaminants (e.g., aggregates and colloids). Depth…

Depth Filters

See also depth filtration for antibody purification Companies:  3 M Purification Depth filters refers to the use of a porous medium that is capable of retaining particulates throughout its matrix…

Inter-alpha inhibitor proteins

Inter-alpha inhibitor proteins (IαIp) are a fmialy of structurally related serine protease inhibitors found at relatively high concentraitons (400-800 mg/L) in human plasma. Unlike other inhiibtor molecules, this fmaily consists…

Antibodies

Antibodies are among the most important classes of proteins involved in the adaptive immune system. Together with T-cell receptors, they provide a robust system of defense agaisnt infeciton caused by…