See also Market Place

StratasysStratasys  3 D Systems (personal systems)    E Ink. Glowforge   (3D laser printers). NCATS 

E-nable (non-profit site)

Biodegradable Scaffolds:

Humacyte uses human vascualr cells which are expanded and seeded onto a biodegradable scaffold made of polymer mesh to create tissues in different diagets and lenghts. The cells prolfierate and build an extracellular matrix (ECM) The cells are fed growth media and subjected to biomechanical stresses. The cells respond and align appropriately in order to generate tissue. Over time, the polymer mesh degrades elaving cells and ECM. Thie proprietary decellularization prcoess removes cells but retains key ECM prtoeins and structure to support biological activity. 

Bioprinting of Tissues and Organs

Bioprinting Companies: Organovo (publically traded bioprinting company; leads market with exvive kidney and liver products) Allegro-3D (San Diego based)  Allevi   CellLink.  

3D bioprinting enables fabrication of scaffolds, devices and tissue models. The most commonly used bioinks for tissue and organ printing are cell-laden hydrogels, decelluarized extracellular matrix solutions and cell suspensions. Cell laden hydrogel bioink formulations use natural hydrogels such as agarose, alginate, chitosan, collage, gelatin, fibrin and hyaluronic acid as well as synthetic hydrogels such as pluronic (poloxamer) and poly(ethylene glycol) (PEG) of blends of both. Typcially hydrogel bioink formualtions reuqire printing of a polymer solution followed by subsequent cross-linking. (Ji “Recent advances in bioink design for 3D bioprinting of Tissues and Organs” 5(23), frontiers in Bioengineering & Biotechnology 2017

3D Printing of Houses

Sunconomy