Introduction: Induced pluripotent stem cells (iPSCs) are stem cells generated form individual somatic cells by exogenous expression of several transcirption factors to initiate the reprogramming process. (Itoh, "Generation of 3D…
Introduction/Definitions: The term "skin" refers to the outer protective covering of the body, consisting of the corium and the epidermis, including sweat and sebaceous glands, as well as hair follicle…
See also Patient induced stem cells Companies: Thermo Fisher Scientific (organoids such as OncoPro Tumoroid Cell oines, stemflex medium for robust expansion of pluripotent stem cells and Geltrex flex matrix…
Introduction: Ichthyosis covers a wide spectrum of diseases affecting the cornification of the skin. All forms of ichthyosis are characterized by extensive scaling, hyperkeratosis, and often inflammation of the skin,…
Introduction: Bacterial meningitis is the leading cause of central nervous system (CNS) infection. The blood–brain barrier (BBB) protects the CNS from most bacteria that may have reached thebloodstream. Most of…
Introduction: Vascular diseases are among the most widespread diseases in the world. Among them, the chronic venous insufficiency (CVI) of the lower limbs represents one of the diseases with higher…
Introduction/Definitions: Chronic pain includes neuropathic pain (e.g., post-surgical and post-herpetic neuralgia), chronic inflammatory pain (e.g., arthritis), and pain of unknown origin (e.g., fibromyalgia). Neuropathic pain is distinguished from nociceptive pain. Neuropathic is pain caused by…
Introduction: The FDA has approved two types of medications for the maangement of Alzheimer's disease: cholinesterase inhibitors and the NMDA-type glutamate receptor inhibitor memantine. These therapies serve to alleviate cognitive…
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