De novo-designed proteins

Free software: AlphaFold (structural protein database; predicts a proteins 3D structure from its amino acid sequence) Openfold3 (collaboration with Nvidia) Latent-X (by Latent Lab is a de novo protein design…

Curcuminoids

See also polyphenols, generally Introduction Definitions: Curcuminoids: may be obtained form or found in a turmeric extract or may be syntehsized. Curcuminoids include curcumin (see below), tetrahydrocurcuminoids (see below), hexahydrocurcuminoids and…

Treatment of Fungal Infections

Introduction: There are four classes of antifungal medicines for invasive fungal disease, and most drugs in these classes are toxic, even at low doses, infectious-disease experts say. A new class…

Meningitis

Introduction: Meningitis is an inflammation of the meninges. The meninges consists of three membranes which encase the soft tissue of the brain and spinal cord. The layers of these membranes,…

Candidiasis

See also treatment of Fungal Infections Candidiasis: Candidiasis is a fungal infection caused by yeast from the genus Candida. Candidiasis can be mucocutaneous or invasive; the most common invasive form…

Probiotics

See also Antioxidants and Polyphenols under "Nutrition & Food" See also intestinal microbiota under bacteria Introduction: Probiotics are living microbial food additives, that have beneficial effect on the microbiological balance…

Agricultural Importance -Bacteria

Citrus Greening Disease (Huanglonbing, HLB): Introduction: Citrus greening disease or Huanglonbing, HLB, is a bacterial plant disease that is spread form one citure tree to the next by a small…

High Consequence Infectious Diseases

Federal Select Agency Program (The Federal Select Agent Program oversees the possession, use and transfer of select agents and toxins, which pose a threat to public, animal or plant health.)…

RNA Vaccines

Introduction: Two different strategies have been pursued for immunotherapy with in vitro transcribed RNA (IVT-RNA), which have both been successfully tested in various animal models. Either the RNA is directly…

Dendritic Cell Vaccines

Definitions: Antigen Sensitized Dendritic Cells: are DCs which have been contacted with an antigen(s) for which an increased immune response is desired. For example, an immature DC (see below) may…