See also Graft or Side Chains/extenders/linkers (Reactive Monomers) The carrier or substrate which is covered in another section (i.e., polysaccharide, polypeptide or silica) is modified by a synthetic polymer which…
References for Commercial Resin types (Tables which include the commercial name/vendor/type of resin): (Ramasubramanyan (US 13/829989) See Tables from Fahrner et al. (US 2003/0229212A1) For another table which lists types of…
Controlled pore glass (CPG) is a media used as a backbone matrix for chromatographic resins. CPG is generally produced form a borosilicate base material that is heated to separate the…
See also "controlled pore glass" as an example of silica in the outline A well described matrix for the purificaiton of proteins is silica. It is commercially available in various…
Typical carrier materials include polysaccharides, polypeptides and silica (Hou, US 4,639,513). Carbonaceous materials Modified carbonaceous materials: Kyrildis (US2002/0056686) teaches that carbonaceous materials such as carbon black, graphite and activated carbon, represent an important…
Type of supports Used There are many different ion exchanger separation supports for biopolymers on teh market. The most common are of beaded type. The particles can be packed in…
Introduction: Cation exchange chromatography refers to a solid phase which is negatively charged, and which thus has free cations for exchange with cations in an aqueous solution passed over or…
See also antibody purification using Anion exchange chromatography under antibody purification and then ion chromatography. Anion exchange is a common process in the recovery of monoclonal antibody products and has been shown to…
Agilent Buffering Advisor Software General Principles: Ion exchange uses an insoluble matrix that carries ionic charges that retard the movement of molecules of opposite charge. There are 2 types, one where…