antibodies

"Polyclonal antibody" refers to an immunoglobulin produced form more than a single clone of plasma cells (e.g., B lymphocytes). Although each B-cellclone produces an antibody which is specific for one particular…

Immunisation of an animal with an antigen results in the production of polyclonal antibodies in other words, different antibodies with different specificities and affinities. A monoclonal antibody refers to an…

As to production of bi-specific antibodies see outline.  Specific Types of BsAbs see outline Introduction: Most natural antibodies are bi or multivalent molecules comprising identical antigen binding sites. The exception are…

Antibody fragments comprise a portion of a full-lenght antibody, as for example, the antigen binding or variable region of a full length antibody.  Antibody fragments that contain the idiotype (antigen-binding fragment)of the…

see also Proteoytic antibodies and IVIG preparations under "protein purification" The terms "abzyme" or "catalytic immunoglobulin" are used to describe antibodies possessing enzymatic activity. Examples of catalytic reactions that may be catalyzed by the…

See also "Fc receptors" under "signal transduction"  See also antibody glycosylation under glycosylation.  See also IgA   Introduction: The term "isotype" refers to the classificaiton of an antibody's heavy or light chain constant region. For example,…

See also "effector functions" of antibodies and also Fc receptors under "signal transduction" Introduction: Functions of Constant Domain The constant domains are not involved directly in binding an antibody to an antigen, but…

See also B cell Development The ability of the immune system to recognize antigens depends on antibodies generated by B cells and on antigen receptors expressed by T cells. These…

HyPare (automatically claculates the impact of mutations on a per-resiude basis for all resiudes of a protein-protein interaction.  An affinity pair is a pair of two molecules that mutually bind with…

IMGT genome database (classifies the immunoglobulin (IG) and T cell receptor (TR) genes from vertebrate species The amino terminal regions of H and L chains are characterized by extensive variability in…