Antibodies in Nature

Immunogetics Information Sytstem Isotypes Expressed Immunoglobulins are expressed in 2 forms: secreted antibody that is produced by plasma cells, and membrane bound antibody that associates with Ig-?/Ig-? heterodimers to form…

Production Techniques

Bispecific Antibodies (See bispecific antibody production under cell expression) The generation of bispecific IgG molecuels is difficult due to the fact that the antigne-bnding sites are built by the variable…

Engineered antibodies

See "homeostasis and half life" of antibodies  See also FcyR structure See also fc receptors under signal transduction web database of mAbs with clinical indications  supplies: Quickchange mutagenesis kit (Agilent Technologies)…

antibody production techniques

Companies: AI screening with AI: OminiAb complete human antibodies: Infinimmune Production of Antibody Fragments: Production of Light chains dimers in E. coli: Rognoni ("A strategy for synthesis of pathogenic human…

therapeutic applications for antibodies

See also Cancer specific antibodies .   See also Wikipedia "List of Therapeutic monoclonal antibodies" Commercially approved antibodies: See the Immunology Link.      web database of mAbs with clinical indications Examples include: (Rituximab or…

Cell expression of Antibodies

Introduction -Definitions: hybridoma fusion and cloning supplement (HFCS): is a low serum containing media supplement for the repalcemetn of fetal calf serum (FCS) in cultures of hybridoma cells. HFCS is specifically…
antibodystructure

Antibody Structure and Types

Figure from Nilsson (US6,740,734B1) Introduction: It is well documented that the structure of an immunogloublin forms a Y-shaped glycoprotein that is composed of two identical heavy and two identical light…

antibodies in nature

Antibodies are proteins that are present on the B-cell membrane and are secreted by plasma cells. Serum antibodies are also sometimes referred to as "immunoglobulins." Antibody functions as the effector…