immunology

United Network for Organ Sharing See also Kidney Diseases  See also MHC In 1901, Landseiner discovered ABO blood group antigens. In 1954, Murray performed the first successful kidney transplant between…

See also non-immune cells (for discussion of osteoblasts and osteoclasts) Osteoporosis; Introduction: Osteoprosis is characterised by a progressive loss of bone mass and microarchitecture which leads to incrased fracture risk.…

 Gram Negative Bacteria as possible agents of bioterroism Botulism: C. botulinum produce botulinum toxins, proteins of MW of about 150,000 which are the most toxic compounds known. There are 7 distinct neurotoxins,…

See CDC classification of Bioterrorism Agents HHS Public Health companies:  Innovatek See Bioterrorism Preparedness Response Act of 2002 for more information on regulations regarding possession and transport of certain agents. Centers for…

Introduction: steps and challenges in eptiope-based vaccine Production In the natural pathogen, there is a plethora of antigens, each comprising tens or hundreds of potentail epitopes. Not all antigens or…

see also B cell maturation and B cell activation B cells recognize native, non-processed antigen and generate antibodies in response to them in contrast to T cells which recognize processed antigen. B cells are antigen-presenting cells. The…

Derivation/Development:  There are NK/T cell progenitors in bone marrow. There is a common T/NK progenitor cell. If this progenitor migrates to thymus, majority will rearrangement and become T cells. However,…

Introduction: Neutrophils comprises in humans 50-70% of all circulating leukocytes, whereas in mice they represent 10-25 of circulating leukocytes. (Rosales "Neutrophils at the crossroads of innate and adaptive immunity". J.…

Granulocytes are innate immune cells that contain specialized granules to provide the first line of immune defense. Upon arrival at the site of infection, they participate in the inflammatory reaction…

Many diseases are characterized by pathogenic autoantibodies such as hemolytic anemia (erythroctye surface antigen), graves' disease (thyroid stimulating hormone R). There are several ways to deal with autoreactive immature B…