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Antibody Purification
Antibody purificaiton schemes
Affinity chromatography of antibodies
specific affinity ligands
protein A/C
conditions
secondary steps
virus inactivation
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by HIC
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carbon filters
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AEX
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by mixed mode chromatography
by hydroxyapatite
by HCIC
by partitioning
by precipitation
affinity precipitation
polyelectrolyte
Anionic
Cationic
Polymer precipitation
smart polymers
particular types of antibodies
antibody fusion proteins
Avion antibodies
IgY isolation
Precipitation agents
ammonium sulfate
IgA
domain antibodies
bi-specific antibodies
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aggregates
charge variants
glycated variants
Extra Light Chains
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Particular Sources for purification
Inclusion bodies
bioterrorism
Common agents of bioterrorism
Analytics & Characterization
next generation sequencing
Common Techniques
Light scattering
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Plasma Proteins
fractionation procedures
Definitions
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albumins
IVIG
ethanol fractionation
ethanol precipitation Steps
chromatography
anion exchange of plasma proteins
cation exchange of plasma proteins
commercial preparations
diagrams
virus inactivation
aggregate/enzyme removal
IgM
IgA
Factor H
Protease Inhibitors
Inter-alpha-Inhibitor Proteins
A1PI
Chromatography
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Buffers
Column Arrangement or Use
Monoliths
expanded bed chromatography
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continuous chromatography
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displacement chromatography
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purification schemes
Affinity Chromatography
IMAC
Lectin Affinity Chromatography
Immunoaffinity
Protein A
Structure
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Temperature senstive mutants
Multimers of SpA domains
Parameters
elution
Resins
methods of coupling ligands to resin
Linkers
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Protein L
Protein G
HIC
Conditions for HIC
RPLC
Small Molecules
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Anion Exchange Chromatography
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types of resins
Specific Types
Silica
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Trade Names
Types of Ligands
Graft Chains
Mixed Mode Chromatography
Types ligands/supports
Hydroxyapatite
Different forms of
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HCIC
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Hemagglutination
DNA diagnostic claims –DNA alles
Ariosa Diagnostics — Petition for rehearing en banc denied –Set up for the Supreme Court?
Ariosa Diagnostics – Diagnostic Method Claims
May 2016 Life Science Examples: Diagnostic claims: Example 29
Treatment Steps in Diagnostic claims
Cleveland Clinic — Diagnostic claims
Diagnostic assays with CRISPR
bioterrorism
Common agents of bioterrorism
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February 9, 2017
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