Papillomaviruses
Papillomaviruses may be classified into distinct groups based on the host that they infect. Structure: Papillomaviruses are small (50-60 nm), nonenveloped, icosahedral DNA viruses that encode for up to 80…
Poxviruses
Poxviruses are large double-stranded, DNA, enveloped viruses. Variola: Variola caused worldwide epidemics. It has been eradicated, although US and Russian laboratories and perhaps others have stocks. 2-10 days post infection, one develops…
KSHV
KSHV is of the and is a lymphotropic herpesvirus. KSHV (also known as human herpesvirus 8 or HHV-8) is associated with the malignancies Kaposi's sarcoma (KS), primary effusion lymphoma (PEL) and plasmablastic variant…
HSV-1 & HSV-2
Herpes Simplex Virus 1 & 2 (HSV-1) are closely related (~50% nucleic acid identity and over 70% amino acid identity) of the alpha subgroup. HSV-1 and HSV-2 initially infect and replicate in mucoepithelial cells and…
Epstein Bar Virus
EBV is of the and infects B cells. It's limited host range (B cells) is due to the limited cellular expression of its receptor which is also the receptor for the…
Herpesviruses
Herpesviruses are large enveloped viruses containing . The viral genome is by and regulated by viral encoded and cellular nuclear factors. Replication of the viral genome is performed by viral encoded . There are 3…
Adenoviruses
Introduction Adenoviruses are naked viruses. Because they have no membrane, they are very stable. Adenoviruses were first identified in 1953 as agents derived from human adenoid tissues which could induce the…
RNA viruses
Global Center for Health Security ArboNet (national srveillnace system for arboviral diseases. Also has information on mosquito borne disesaes) RNA viruses remain in the cytoplasm except for retroviruses. RNA viruses…
DNA viruses
Introduction: Transcription of the DNA virus genome (except for poxviruses) occurs in the nucleus. Many DNA viruses establish persistent infections. DNA viruses use the cellular RNA polymerase to produce mRNA.…
Viruses
NYC Public Health testing laboratory manual (good resource for types of viral and bacterial diseases and tests used to identify them) Global Center for Health Security Introduction; Definitions: Viruses come…