Treatment of Alzheimer’s disease

Introduction: The FDA has approved two types of medications for the maangement of Alzheimer's disease: cholinesterase inhibitors and the NMDA-type glutamate receptor inhibitor memantine. These therapies serve to alleviate cognitive…

Biosimilars

The pipeline of follow-on (biosimilar) products in developmetn includes nearly 800 biosimilars. See Biosimilarspipeline Guidance for Industry: Clinical Pharmacology Data to Support a Demonstration of Biosimilarity to a Reference Product, May…

Expedited Drug Approval

Guidance for industry Expedited Programs for Serious Conditions – Drugs and Biologics (May 2014) The FDA has several programs which are intended to facilitate and expedite development and review of…

Skin Disorders

Contact Dermatitis: Contact dermatitis is a common inflammatory skin condition characterized by erythematous and pruritic skin lesions that occur after contact with a foreign substance. There are two forms of…

Treatment of Fungal Infections

Introduction: There are four classes of antifungal medicines for invasive fungal disease, and most drugs in these classes are toxic, even at low doses, infectious-disease experts say. A new class…

Meningitis

Introduction: Meningitis is an inflammation of the meninges. The meninges consists of three membranes which encase the soft tissue of the brain and spinal cord. The layers of these membranes,…

High Consequence Infectious Diseases

Federal Select Agency Program (The Federal Select Agent Program oversees the possession, use and transfer of select agents and toxins, which pose a threat to public, animal or plant health.)…

COPD

COPD is a group of diseases characterized by limitation of airflow in the airway that is not fully reversible. COPD is the umbrella term for chronic bronchitis and/or emphysema.  In COPD the airways…

Diagnosis of Eye Diseases

Bascam Eye Center Defintions: A-scan: Interferometry works by splitting a light beam and comparing it with a reference beam. When the beams interfere, they create an interference pattern, which is then…

STDs

CDC (clinical guidance for STIs) Chancroid: Cause: Chancroid is caused by a pleomorphic gram-negative rod called Haemophilus ducreyi. Symptoms: this ulcerative disease usually beings as a soft apule, or bump, at the point…