diseases and disorders

Introduction: Ichthyosis covers a wide spectrum of diseases affecting the cornification of the skin. All forms of ichthyosis are characterized by extensive scaling, hyperkeratosis, and often inflammation of the skin,…

Introduction: Bacterial meningitis is the leading cause of central nervous system (CNS) infection. The blood–brain barrier (BBB) protects the CNS from most bacteria that may have reached thebloodstream. Most of…

Introduction: The FDA has approved two types of medications for the maangement of Alzheimer's disease: cholinesterase inhibitors and the NMDA-type glutamate receptor inhibitor memantine. These therapies serve to alleviate cognitive…

The pipeline of follow-on (biosimilar) products in developmetn includes nearly 800 biosimilars. See Biosimilarspipeline Guidance for Industry: Clinical Pharmacology Data to Support a Demonstration of Biosimilarity to a Reference Product, May…

Guidance for industry Expedited Programs for Serious Conditions – Drugs and Biologics (May 2014) The FDA has several programs which are intended to facilitate and expedite development and review of…

See also Skin Introduction: Millions of people suffer from skin dieseases. In the U.S. almost 85 million Americans were seen by a physician for at least one skin disease in…

Introduction: There are four classes of antifungal medicines for invasive fungal disease, and most drugs in these classes are toxic, even at low doses, infectious-disease experts say. A new class…

Meningitis Research Foundation (research foundation) Introduction: Meningitis is an inflammation of the meninges. The meninges consists of three membranes which encase the soft tissue of the brain and spinal cord.…

Federal Select Agency Program (The Federal Select Agent Program oversees the possession, use and transfer of select agents and toxins, which pose a threat to public, animal or plant health.)…

COPD is a group of diseases characterized by limitation of airflow in the airway that is not fully reversible. COPD is the umbrella term for chronic bronchitis and/or emphysema.  In COPD the airways…