structural characterization of proteins

AlphaFold (put in amino acid sequence and obtain predicted 3D structure) More than 540,000 protein sequences have been deposited in the nonredundant database maintained by the National Center for Biotechnology…

Protein bioinformatics

Useful Links:  Human Proteome Map Portal contains translation of protein products derived from over 17k human genes.   Proteomic Data Base   world-wide Protein Data Bank (contains more than 126,000 experimentally determiend atomic level 3D structures…

Metabolomics

See also bacterial metabolism Metabolomics is the study of the entire complement of all the small molecular weight metabolites inside an organism of interest. Some metabolites which are routinely assayed in the…

Glycomics

See also Lectin Affinity chromatography under Affinity Purification  Definitions Glycan: refers to the carbohydrate portion of a glycoconjugate, such as a glycopeptide, glycoprotein, glycolipid or proteoglycan. Regnier (US8,568,993)  Glycomics is the systematic…

Editing genomes

See also CRISP gene editing under Enzymes and endonucleases Gene editing refers to the introduction of desired changes at specific genomic loci. The original strategy for gene editing was to use…

functional assessment of non-coding DNA

Once conserved non-coding sequences (CNSs) regions have been identified, the next step is to evaluate their function in biological experiments. There are various techniques to assess regulatory function. DNASE I…

analysis of the genome

Cross-References: Protein Bioinformatics DNA/RNA Bioinformatics ---------------------------------------------------------------------------------------------- DNA Databases BLAST Genbank at NCBI EMBL DNA DDBJ http://www.ncbi.nlm.nih.gov/LocusLink/" style="color: rgb(146, 172, 186); -webkit-transition: background-color 0.2s ease-in-out, color 0.2s ease-in-out; transition: background-color 0.2s ease-in-out, color 0.2s ease-in-out;">LocusLink (NCBI) Sequence…

DNA/RNA bioinformatics

Cross-References: Protein Bioinformatics Genome Bioinformatics =========================================================================== Annotation: Seqvista Condons:  Codon Table ESTs/Tandom Repeats: EST Extractor EST Sequence Database (NCBI) TGEM EST Assembly Machine Immunoglobulins: IMGT (links of CDR analysis and sequence alignment) Primers: Primer3 Primer3 (MIT) Primer generator for mutagenesis Tandom Repeat…

Bioinformatics

Bioinformatics is the application of information technology to the management and analysis of biological data with the aid of computers. Bioinformatics can be divided into 3 major divisions: 1) DNA/RNA,…

MRSA & other dangerous bacteria

See also Antibiotics and bioterrorism agents Antibiotic resistance is a serious threat in the clinic with a variety of infectious bacteria possessing resistance to commonly used antibiotics. Of particular concern…