Bioinformatics

Bioinformatics is the application of information technology to the management and analysis of biological data with the aid of computers. Bioinformatics can be divided into 3 major divisions: 1) DNA/RNA,…

MRSA & other dangerous bacteria

See also Antibiotics and bioterrorism agents Antibiotic resistance is a serious threat in the clinic with a variety of infectious bacteria possessing resistance to commonly used antibiotics. Of particular concern…

intestinal microbiota

See also Probiotics Introduction: The intestinal microbiota is confined most to the colon where some 1.5 kg of microbes or 1014 microorganisms reside. There are more genes in the human…

Bacterial toxins

Introduction: Secretion of toxins is s a primary way bacteria cause disease. There are 2 types of toxins; endotoxins and exotoxins. Endotoxins: Endotoxins are found only in  gram-negative bacteria. ndotoxins…

Disease mechanisms

See also Antibiotic Resistance Mechanisms Videos: Anthrax  Anthrax2 (types) Anthrax (endospores)  E. coli (virulent strain) C. Difficile (sniffing dogs)  Endotoxins (description) Inside the Phagosome (e.g., TB) Tetanus (spores) Tetanus (Brigham;…

Bacterial metabolism

See also metabolism Videos: nitrogen fixation  Introduction: Distinct metabolic strategies allow microbes to extract energy from diverse surroundings and colonize nearly every part of the earth. Microbial energy metabolisms vary…

Syphillis

Treponema pallidum, formerly known as Spirochaeta pallida, is a microaerophillic spirochaete bacterium with subspecies that cause the diseases syphillis, bejel (also known as endemic syphillis) and yaws, which are morphologically and…

host response to Legionella

Innate Responses to Lp Upon entering macrophages, Lg replicate. But Macrophages mount response which induce pro-inflammatory cytokines (Il-12, IL-1 B, TNF, IL-1B, chemokines). Il-12 is important important because activates NK…

Legionella CFUs

Colony forming unit (CFU): refers to individual colonies of bacteria, yeast or mold. A colony of bacteria or yeast refers to a mass of individual cells of the same organism, growing…

legionella streaking

(1) get w black agar plates (Jimmy makes it); (use 2 plates just in case 1 does not grow)  label LP on back of plate with Date and strain #.…