Glycomics

See also Lectin Affinity chromatography under Affinity Purification  Definitions Glycan: refers to the carbohydrate portion of a glycoconjugate, such as a glycopeptide, glycoprotein, glycolipid or proteoglycan. Regnier (US8,568,993)  Glycomics is the systematic…

Editing genomes

See also CRISP gene editing under Enzymes and endonucleases Gene editing refers to the introduction of desired changes at specific genomic loci. The original strategy for gene editing was to use…

functional assessment of non-coding DNA

Once conserved non-coding sequences (CNSs) regions have been identified, the next step is to evaluate their function in biological experiments. There are various techniques to assess regulatory function. DNASE I…

analysis of the genome

Cross-References: Protein Bioinformatics DNA/RNA Bioinformatics ---------------------------------------------------------------------------------------------- DNA Databases BLAST Genbank at NCBI EMBL DNA DDBJ http://www.ncbi.nlm.nih.gov/LocusLink/" style="color: rgb(146, 172, 186); -webkit-transition: background-color 0.2s ease-in-out, color 0.2s ease-in-out; transition: background-color 0.2s ease-in-out, color 0.2s ease-in-out;">LocusLink (NCBI) Sequence…

DNA/RNA bioinformatics

Cross-References: Protein Bioinformatics Genome Bioinformatics =========================================================================== Annotation: Seqvista Condons:  Codon Table ESTs/Tandom Repeats: EST Extractor EST Sequence Database (NCBI) TGEM EST Assembly Machine Immunoglobulins: IMGT (links of CDR analysis and sequence alignment) Primers: Primer3 Primer3 (MIT) Primer generator for mutagenesis Tandom Repeat…

Bioinformatics

Bioinformatics is the application of information technology to the management and analysis of biological data with the aid of computers. Bioinformatics can be divided into 3 major divisions: 1) DNA/RNA,…

MRSA & other dangerous bacteria

See also Antibiotics and bioterrorism agents Antibiotic resistance is a serious threat in the clinic with a variety of infectious bacteria possessing resistance to commonly used antibiotics. Of particular concern…

intestinal microbiota

See also Probiotics Introduction: The intestinal microbiota is confined most to the colon where some 1.5 kg of microbes or 1014 microorganisms reside. There are more genes in the human…

Bacterial toxins

Introduction: Secretion of toxins is s a primary way bacteria cause disease. There are 2 types of toxins; endotoxins and exotoxins. Endotoxins: Endotoxins are found only in  gram-negative bacteria. ndotoxins…

Disease mechanisms

See also Antibiotic Resistance Mechanisms Videos: Anthrax  Anthrax2 (types) Anthrax (endospores)  E. coli (virulent strain) C. Difficile (sniffing dogs)  Endotoxins (description) Inside the Phagosome (e.g., TB) Tetanus (spores) Tetanus (Brigham;…