Transplantation

United Network for Organ Sharing Companies: eGeneis (developing porcine organs for transplant) See also Kidney Diseases  See also MHC In 1901, Landseiner discovered ABO blood group antigens. In 1954, Murray…

Light scattering

Companies:  ALV.  Brookhaven Instruments   Malvern. Wyatt   Light scattering is one of the few absolute methods available for the determination of molecular mass and structure and is applicable over a broader…

Mas spectrometry

Mass spectrometry (MS) has gained importance in the anlytics of biopharmaceuticals, taking different complementary approaches ranging from peptide-based sequencing to direct analysis fo intact proteins and protein assmeblies. (Rosati, Nature…

Chimeric antigen receptors (CARS)

Websites:  ClinicalTrials.gov  (lists many active CART trials). See also Enzymes and CRISP Introduction to CARs/CARTs and TCRs Chimeric antigen receptors (CARs) are engineered receptor proteins, while chimeric antigen receptor T…

Tumor immunology

Tumour Immunology Strategies cancer vaccines refers to therapeutic immunization in patients with cancer, with the main aim of breaking tolerance toward self-tumor-associated antigens. One strategy is to pulse antigen presenting cells…

Chemotherapy

MedlinePlus Most, if not all, chemotherapeutic agents kill cancer cells through the induction fo apoptosis. Specific Chemotherapeutic agents Colchicine: has been investigated as an anti-cancer agent and has proven to be…

Treatment for cervical cancer

Treatment of invasive cervical cancer is affected by the stage of the disease, which is based on clincal evaluation. Chemotherapy:  Single-agent chemotherpay can be divided into those who received plantinum-based therapy…

Cancer specific antibodies

See also therapeutic applications of antibodies   See also Antibodies as toxic drug carriers in drug delivery.  Companies:  Immunogen Often membrane-associated polypeptides are specifically expressed on the surface of one or more particular type(s)…

Treatment of cancer

MedLinePlus Frederick National Laboratory Unpredictability in Cancer Treatment Non-correlation between In Vitro and In Vivo treatment: Cancer treatment is highly unpredictable. For example, even though the EGFR was identified in some…

Bone & Joint Diseases

See also non-immune cells (for discussion of osteoblasts and osteoclasts) Osteoporosis; Introduction: Osteoprosis is characterised by a progressive loss of bone mass and microarchitecture which leads to incrased fracture risk.…