Immunogenicity
Factors which Determine Immunogenicity Immunogenicity is the ability to induce a humoral and/or cell mediated immune response. Although a substance that induces a specific immune response is usually called an "antigen" the more…
Nucleic acid vaccination
Companies: Osivax Nucleic acid based immunization exhibits a number of advantages. For example, the manufacture of nucleic acid based vaccines is straight forward, relatively inexpensive. DNA Vaccines Potential advantages: DNA based…
Active Immunization
See "ways to increase immunogenicity" on outline See WHO See History of Vaccines Active immunization refers to stimulation of an immune response by challenge with an immunogen. Active immunization occurs…
Vaccines & Immunization
helpful websites: NIH Vaccines Immunisation Immunisation Guidelines for Ireland 2008 Edition, Royal College of Physicians of Ireland (good summary of all of the vaccine schedules) GAVI: the vaccine alliance International Society of Travel…
Viral sensing proteins
Cellular RNA is usually unable to activate the immune response, with several modifications protecting self-RNA from being recognized by pattern recognition receptors in the cytoplasm, under the normal conditions described.…
COVID-19
Websites of interest: Coronavirusgov. Travel Restrictions. Covid treatments CDC case tracker CDC covid-19 county check (check levels of Covid-19 in your county) Find Covid-19 Medications and clinics (rapid treatment of COVID-19 is…
Coronaviruses
Coronaviruses are a large family of viruses. Some cause illness in people, and others, such as canine and feline coronaviruses only infect animals. Coronaviruses include enveloped viruses and cause the…
Respiratory Viruses
See also Coronaviruses (family Coronaviridae) Cleaning Respiratory Equipement Adenoviruses (see outline) Hantaviruses Hantaviruses comprise an emerging global threat for public health, affecting about 30,000 humans annually. Infection may lead…
Myocarditis
Treatment: (I) Immunoglobulin therapy: Kishimoto et al. (j Pharmacology, 299(2), 2001) demonstrated the immunoglublin therapy suppressed murine myocarditis induced by cosachievirus B3. Matsumori et al. ("Effects of Free Immunoglobulin light chains…
Cancer disease mechanisms
See also Cell Cycle Control Introduction/Definitions: Cancer involves a host of different pathogenic mechanisms which lead to cancer cells evading a host immune response. These mechanisms or abnormalities are important…