Alterations in chromatin structure

See also Chromosomes and DNA Methylation and deMethylation and role of Epigenetic Modifications in Driving Th1/Th2 Development and Fetal Assays based on Chomatin epitopes and Histone aceylation. A large number of covalent modifications of histones have been…

RNA capping & splicing

RNA Capping: In eukaryotes, transcription is only the first step leading up to a mature mRNA which can be transported out of the nucleus to the cytoplasm of the cell…

Regulation of transcription

See also transcription Comparative genome analyses indicate that increases in gene number do not account for increases in morphological and behavioral complexity. For example, the nematode worm has about 20,000…

Transcription

See also RNA capping and splicing Transcription in eukaryotic cells occurs in the nucleus followed by translation in the cytoplasm. Transcription is the transfer of information from a double stranded…

Prions

Prions cause spongiform encephalopathies which are uniformly fatal. They have a long period from exposure to manifestation of disease (1-2 years). A variant form of the prion protein PrP-27C called PrP-27Scis required…
codon table

Amino acid table

Amino Acid Table Amino Acid 3-letter Code 1-letter code Side chain (R) Alanine   Ala  A  -CH3 Arginine  Arg  R  -(CH2)3NHCHNH2NH2+ Asparagine  Asn  N -CH2CONH2 Aspartic Acid   Asp   D  -CH2COOH Cysteine  Cys…
biopro1

Protein structure

Proteins are polymers of amino acids. Each amino acid consists of an amino group, a carboxyl group, a H atom and a distinctive R group all of which are bonded…

DNA replication

DNA replication is semi conservative in that each DNA molecule produced consists of 1 old and 1 new partner. The reason for this semi conservative nature is that the original DNA strands…

SNPs

SNPS are particular nucleotide sequences that are repeated within a region of a DNA strand (called an STR locus). STR loci occur frequently in the human genome, and the number…

Genetic polymorphisms

Applied Genetics Group at NIST (characterization of genetic polymorphisms) Polymorphisms are variations in a person's DNA sequence. These may occur in an exon and result in a difference in the protein…