Recombination
New sequences of nucleotides can be generated in DNA not only by mutation, but also by the formation of new arrangements of genes by the movement of blocks of DNA.…
Genetics
Companies: 23andme (provides kits for heritage and may offer health related kits in future) Human genetics is the study of heredity in human beings. The human genome, the entirety of human…
DNA forensics
DNA forensics is the application of DNA technology to law enforcement and crime.
DNA repair
Maintaining genetic stability requires not only accurate ways to replicate DNA but also mechanisms to repair damage that occurs to DNA. The importance of such repair mechanisms is illustrated by…
DNA
See also chromosomes Materials: DNA Extraction: Wizard Genomic DNA purificaiton kit (Promega, A2361). (Kamimura, US Patent Application No: 16/484,061, published as US 2019/0359691) PCR Product Purification: QIAquick PCR purificaiton kit (Qiagen,…
Transgenic mice
GTC-Bioterapeutics Transgenesis has become a major tool for biologists. Although most genetically modified animals such as mice are generated for basic sutdies, physiology and pathology of farm animals such as pigs,…
Knock-out mice
Introduction: A "knockout" animal has had a gene inactivated so that the funciton of the gene is lost. It is possible to inactivate genes in a number of different experimental…
Mice
References: "Anatomy of Mouse" Mice are the mainstay of in vivo immunological experimentation and in many respects they mirror human biology remarkably well. This conservation of function is reflected on the…
Animal models
Disease Modeling: GD Genesis (preclinical models of human disease) Alta Sciences (preclinical research services) Humanized mice: Genoway (reconsititued human mouse) AbTherx (transgenic mice for antibody discovery) Research in biotechnology and…
Biotechnology
Biotechnology (sometimes shortened to "biotech") is a field of applied biology that involves the use of living organisms and bioprocesses in engineering, technology, medicine and other fields requiring bioproducts. Biotechnology…