next generation sequencing

Agilent Technologies.     Element Biosciences.   Illumina. MGI Tech. Oxford Nanopore Technologies  PacBioPacBio. Qiagen. Roche. Singular Genomics Thermo Fisher Scientific Ultima Genomics  Twist Biosciences single cell sequencing: 10x Genomics (conoply biosciences) (single…

single domain

Nanobody® is a registered trademark of Ablynx N.V. Definitions: VHH refers to an antibody single variable domain (VH or VL) polypeptide that specifically binds antigen. While the antigen binding unit of…

IgG

IgG homeostasis: (see right hand panel) IgG participates in defending against viral antigens, whereas IgM is predominantly active in antibacterial and antitoxin immune responses (US2013/0052208).  Antibodies belong to a family of…

IgA

companies:  Secretory IgA  IgA synthesis exceeds the combined total of all the other immunoglobulin classes.  Where IgA is found, Generally IgA may be monomeric (i.e., a single molecule), dimeric (composed of two…

Cytokines & Chemokines

For a nice list of monoclonal antibodies currently on the market see (Shukla, "Recent advances in large-scale production of monoclonal antibodies and related proteins" Trends in Biotechnology, 28(5) pp. 253-261)…

complement components

Antibodies to Complement Pathway Components Preclinical studies using animal models and human derived samples demonstrate that inhibition of complement ameliorates many inflammatory and autoimmune disease manifestations. The AP pathway has…

specific disorders

For therapeutic applications of IL-6 antibodies see IL-6 under "immunology" For cancer specific antibodies see the "cancer" section Cancer and Lymphomas: The first antibody for the treatment of cancer was a chimerica…

bi-specific antibody production & isolation

As to Bispecific antibodies generally see Bispecific antibodies under structure and types As to Be-specific antibody purificaiton see bi-specific antibodies under particular types of antibodies purified see also Engineering of…

polyclonal antibody production

To constrain costs, strategies have been developed to produce recombinant polyclonal antibodies in a single pot. This process by passes the manufacturing hurdles assocaited with individual antibody production but introduces…

monoclonal antibody production

See also Immunization and ways to increase immunogenicity                See also B cell activation . See also cell culture in Biotechnology Introduction Since the development of the hybridoma technology by Kohler and Milstein 35…