Common Analytical Techniques
Differential scanning calorimetry (DSC) can be used to examine the stability of the tertiary structure of antibody preparations. (Brass, Pharm Acta Helv. 1996, 71(6): 395-403) Immunoassay (ELISA): can be used to…
Waste Water Treatment
Septic Systems Many rural and suburban areas rely on septic tanks which are containers into which sewage flows. The solid material settles and is subject to microbial decomposition. The liquid…
continuous chromatography
See also simulated moving bed chromatography (this is a form of continuous chromatography) under moving bed. Definitions: Binding capacity and mass transfer: The binding capacity strongly depends on the affinity…
Peptides and Mimotopes
Companies: Abreos Biosciences Links of interest: Mimo DB Definitions Anti-Idiotype antibody: binds to the idiotype of another antibody, usually an antibody drug. Idiotype: is the sepcific combination of idiotopes present…
Linkers
Attachment of Protein A to a solid support, Generally Methods of attaching protein ligands sucha s protein A and G to a solid support include ativating a media with a…
Blood Purification
Companies: Haemonetics Apheresis (cytapheresis and Plasmapheresis): Conventional apheresis methods include centrifugation, which can separate any of the components of the blood, and membrane filtration, which can be used for plasmapheresis…
Protein L
See also Continuous Chromatography under Chromatography, Column arrangement. Commercial Protein L Resins: Capto L (GE Healthcare Life Sciences) Data file 29-0100-08 AB) combines a rigid, high flow agarose matrix with…
By Hydrophobic Resins & Activated Carbon
See also Carbon Filters Companies: Merk Group: Merck KGaA (subsidiaries: EMD Millipore Corporation) Separation of Antibodies using Hydrophobic Chromatography Resins Polystyrene or poly(ethyl)styrene or Vinylbenzene: --cross-linked with Copolymers od divinylbenzene…
antibody production techniques
Companies: AI screening with AI: OminiAb complete human antibodies: Infinimmune Pharmaology: JAX HuPK (FcRn PK) Platform (an in-vivo tool that provides translationally relevant PK data (half life Cmax, etc) of…
therapeutic applications for antibodies
See also Cancer specific antibodies . See also Wikipedia "List of Therapeutic monoclonal antibodies" Commercially approved antibodies: See the Immunology Link. web database of mAbs with clinical indications Examples include: (Rituximab or…