Integrins

January 16, 2022Posted inCell Biology
Integrins are widely expressed cell surface adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. Integrins are the principal receptors on animal cells for binding most  like collagens, fibronectin and laminins. T…

Cell junctions

January 16, 2022Posted inCell Biology
A basic feature of multicellular animals is the formation of diverse kinds of tissue, such as skin, blood, or muscle, where cells are organized in specific ways. Cells must also…

Cell adhesion

January 16, 2022Posted inCell Biology
Cells adhere to each other and to the extracellular matrix through cell surface proteins called cell adhesion molecules (CAMs). Tissue architecture is established and maintained to a large extent by…

Stem cells

January 16, 2022Posted inCell Biology
CIRM  US Stem cell  NIH  NOVA   International Society for Stem Cell Research Aging and Brain Repair (USF Health) Companies: Stem Genomics Introduction: A stem cell is defined by its ability to undergo asymmetric…

Non-immune cells

January 16, 2022Posted inCell Biology
Within the bone marrow, all blood cells originate from a single type of unspecialized cell called a stem cell. When a stem cell divides, it first becomes an immature red…

Types of cells

January 16, 2022Posted inCell Biology
Over 200 different cell types in the human are known. The most numerous are the red blood cells, then platelets/thrombocytes and 3) white blood cells or leukocytes. These cells form a variety of different tissues.…

Translation

December 26, 2021Posted inBiotechnology
Companies: Tevard Biosciences (TRNA therapies) See Prokaryotics for differences with their translation Translation is the process of converting the nucleotide sequence of mRNA into a protein. This is accomplished in…

Histone acetylation

December 26, 2021Posted inBiotechnology
There is evidence that histoe acetylation and deacetylation are mechanisms by which transcriptional regulation in a cell is achieved (Grunstein, M. (1997) Nature 389: 249-52). These effects are throught to…

Methylation & demethylation

December 26, 2021Posted inBiotechnology
For Histone methylation see right hand panel. Epigenetics has two main elements; DNA methylation and histone modifications. Transcriptional activation of tissue-specific genes generally involves both DNA demethylation and changes in chromatin structure,…