Cell Biology
Cell Biology is the study of cells such as their structure, property and interactions.
Translation
Companies: Tevard Biosciences (TRNA therapies) See Prokaryotics for differences with their translation Translation is the process of converting the nucleotide sequence of mRNA into a protein. This is accomplished in…
Histone acetylation
There is evidence that histone acetylation and deacetylation are mechanisms by which transcriptional regulation in a cell is achieved (Grunstein, M. (1997) Nature 389: 249-52). These effects are thought to…
Methylation & demethylation
For Histone methylation see outline. See also Regulation of Transcription. Epigenetics Epigenetics has two main elements; DNA methylation and histone modifications. Transcriptional activation of tissue-specific genes generally involves both DNA demethylation…
Alterations in chromatin structure
See also Chromosomes and DNA Methylation and deMethylation and role of Epigenetic Modifications in Driving Th1/Th2 Development and Fetal Assays based on Chomatin epitopes and Histone aceylation. A large number of covalent modifications of histones have been…
RNA capping & splicing
RNA Capping: In eukaryotes, transcription is only the first step leading up to a mature mRNA which can be transported out of the nucleus to the cytoplasm of the cell…
Regulation of transcription
See also transcription Comparative genome analyses indicate that increases in gene number do not account for increases in morphological and behavioral complexity. For example, the nematode worm has about 20,000…
Transcription
See also RNA capping and splicing Transcription in eukaryotic cells occurs in the nucleus followed by translation in the cytoplasm. Transcription is the transfer of information from a double stranded…
Prions
Prions cause spongiform encephalopathies which are uniformly fatal. They have a long period from exposure to manifestation of disease (1-2 years). A variant form of the prion protein PrP-27C called PrP-27Scis required…
Amino acid table
Amino Acid Table Amino Acid 3-letter Code 1-letter code Side chain (R) Alanine Ala A -CH3 Arginine Arg R -(CH2)3NHCHNH2NH2+ Asparagine Asn N -CH2CONH2 Aspartic Acid Asp D -CH2COOH Cysteine Cys…