biobon1

Bonds

Definitions: Oxidation refers to where electrons are transferred from one atom to another. The molecule that gives up electrons is said to be Oxidized and is also called a reductant because it is reducing another…

Siglets

See also Glycan Binding Proteins Sialic acid (Sia)-binding Ig-like lectins (Siglecs) are a family of glycan-binding proteins (GBPs). They are an immunoglobulin super family lectins with a defining feature of recognizing sialic acid containing structures.…

Glycoforms

Raju "Glycosylation Variations with Expression Systems and their impact on biological activity of therapeutic immunoglobulins" BioProcess International, April 2003 Fig. 4 above shows the largest N-linked oligosaccharide structure found in…

ABO System

See also determining ABO Blood type   See also galactosidases   See removing A/B antigens from blood cells Blood group antigens are either sugars or proteins, and they are attached to various components in the…

Lectins

Lectins are glycoproteins that can bind carbohydrates. These carbohydrate binding proteins serve a number of vital roles which are disucussed below. Classification There are a number of structurally distinct plant and animal…
glycosylation 1

Antibody glycosylation

As to purification of glycosylated antibodies see "antibody purification" and "glycan antibody" under "particular types" See also Function of Glycosylation:  (see outline)   from WO 2007/024743 A2 from US 14/352,411 Antibodies are glycoproteins…

Serine Protease Inhibitors

Serine protease inhibitors or "serpins" form a large family of inhibitors that regulate various physiological processes such as angiogenesis, neoplasmia, apoptosis, inflammation, coagulation, fibrinolysis and viral pathogenesis. Dysfunction of such…

Cationic polymers

See also Drug Deliver where cationic polymers have been sued.  Naturally derived Cationic Polymers Cellulose: (C6H10O5)n  is a polysaccharide consisting of a linear chain of several hundred to many thousands of…

Ligand gated

Ligand gated ion channels/receptors are large multisubunit complexes which are usually pentamers (5 subunits) that form an ion channel in the membrane. The complex may be heteromeric in that it is composed…

Types of hormones

See also Hormones, generally  See also Signal transduction Hormones may be categorized as lipophilic (fat-soluble), which are nonpolar, or hydrophilic (water-soluble), which are polar. The lipophilic hormones include the steroid…