Engineered antibodies

See "homeostasis and half life" of antibodies  See also FcyR structure See also fc receptors under signal transduction web database of mAbs with clinical indications  supplies: Quickchange mutagenesis kit (Agilent Technologies)…

Common Analytical Techniques

  Differential scanning calorimetry (DSC) can be used to examine the stability of the tertiary structure of antibody preparations. (Brass, Pharm Acta Helv. 1996, 71(6): 395-403)  Immunoassay (ELISA): can be used to…

Waste Water Treatment

Septic Systems Many rural and suburban areas rely on septic tanks which are containers into which sewage flows. The solid material settles and is subject to microbial decomposition. The liquid…

continuous chromatography

See also simulated moving bed chromatography (this is a form of continuous chromatography) under moving bed.  Definitions: Binding capacity and mass transfer: The binding capacity strongly depends on the affinity…

Peptides and Mimotopes

Companies: Abreos Biosciences Links of interest: Mimo DB Definitions Anti-Idiotype antibody: binds to the idiotype of another antibody, usually an antibody drug.  Idiotype: is the sepcific combination of idiotopes present…

Linkers

Attachment of Protein A to a solid support, Generally Methods of attaching protein ligands sucha s protein A and G to a solid support include ativating a media with a…

Blood Purification

Companies:  Haemonetics Apheresis (cytapheresis and Plasmapheresis): Conventional apheresis methods include centrifugation, which can separate any of the components of the blood, and membrane filtration, which can be used for plasmapheresis…

Protein L

See also Continuous Chromatography under Chromatography, Column arrangement. Commercial Protein L Resins: Capto L (GE Healthcare Life Sciences) Data file 29-0100-08 AB) combines a rigid, high flow agarose matrix with…

By Hydrophobic Resins & Activated Carbon

See also Carbon Filters Companies:  Merk Group:  Merck KGaA   (subsidiaries: EMD Millipore Corporation) Separation of Antibodies using Hydrophobic Chromatography Resins   Polystyrene or poly(ethyl)styrene or Vinylbenzene: --cross-linked with Copolymers od divinylbenzene…

antibody production techniques

Companies: AI screening with AI: OminiAb complete human antibodies: Infinimmune Production of Antibody Fragments: Production of Light chains dimers in E. coli: Rognoni ("A strategy for synthesis of pathogenic human…